Category Archives: cannabis brownies
MEDICAL MARIJUANA: MISCONCEPTIONS ABOUT ALTERNATIVE MEDICINE
MEDICAL MARIJUANA: MISCONCEPTIONS ABOUT ALTERNATIVE MEDICINE
BY: Natalie Gray
Medical marijuana or MMJ has been used for decades now to help people afflicted with serious medical conditions that include, but are not limited to glaucoma, cancer, epilepsy, AIDS, and MS (Multiple Sclerosis). As one of the most effective agents that help people cope with chronic pain, medical marijuana offers patients relief from extreme discomfort by alleviating their symptoms.
Understanding the Science Behind Medical Marijuana
Understanding the science behind the effectiveness of marijuana is important in order to dispel these myths and make a well-informed choice about what it truly offers. When administered under the supervision of a qualified and competent doctor or medical practitioner, medical marijuana reduces the pain and nausea that various health problems cause. Scores of people believe that medical marijuana is extremely addictive, and it increases the dependency on the drug.
Research indicates that there is no evidence to support this belief because to start with, medical cannabis does not even have any chemicals that may trigger addiction in people who use it as a part of their treatment process. Then there are other misconceptions that MMJ may also lead to the use of hard drugs such as cocaine and like the former, this is also just a misconception. While medical marijuana can be smoked like a regular banana kush, this is not the only way that it can be used.
There are mainly two types of cannabinoid receptors; CB1 and CB2 that trigger a cascade of biological events within them. While the former type is mainly found in the nerve cells of the brain and is responsible for the mind altering effects of cannabis, the latter is found all over the body and it could be the prime suspect that triggers the biological effects of these cannabinoids on the other parts of the body apart from the brain. So, designing suitable drugs based on the active ingredients that are found in hash oil may be important for the treatment of cancer.
Medical Marijuana As Alternative Medicine
Right from prescription drugs and pills that contain synthetic forms of medical marijuana to other alternate treatment methods, cannabinoids such as THC can be delivered to the body without smoking MMJ. The marijuna seeds, flowers and leaves can be soaked in a mixture of alcohol to extract the cannabinoids in marijuana. This infusion can either be added to drinks and food or absorbed through skin patches and in this form; it takes MMJ as little as a half hour to produce the desired effect. The active components can also be transferred into cooking oil and butter by simmering the plant in them for several hours. This is usually used to bake cookies and brownies or make other types of food that a patient might find appetizing.
Thought there are tests that show that Medical cannabis can cause short term memory loss in some patients who are undergoing treatment, the truth is that the effect is only temporary. Medical marijuana neither reduces their intelligence nor does it affect their long-term memory. Though medical cannabis is an all-natural substance that is obtained from plants, the misconceptions about it are quite controversial and baseless.
Medical Marijuana Works at A Fundamental Level
It is amazing that smoking cannabis works so much better than many pharmaceuticals, which are always absorbed through the proper medium. By setting a plant on fire, inhaling the resulting smoke, and blowing it out, much more relief can be found than ingesting a pharmaceutical substance that decades of research was put into.
The fact that smoking cannabis works better than pharmaceuticals is a testament to its place as humanity’s greatest medicine, but what really matters are the effects people have been having with extract medicine. There is an entire movement working to spread the truth that extracts are capable of curing/eliminating or completely controlling serious diseases like cancer, heart disease, arthritis, Crohn’s, chronic pain, IBS, hepatitis C, multiple sclerosis, Parkinson’s, mental disorders, and more.
Cannabis works against so many conditions because it functions at a fundamental level, restoring balance to all body systems. Since all disease is an imbalance of some kind, cannabis is the best herb for restoring balance.
Bottom Line
Cannabis is one of the most medicinal plants in the world, and when prepared into extracts, its true power is released. The main problem with the medicinal cannabis movement at this point in time is its focus on smoking marijuana, or even vaporizing it. The bottom line is that’s not the right way to use cannabis as a medicine, as effective as even that can be., and its effects greatly exceed what smoked marijuana could ever achieve. Medicine is not intended to be absorbed in a low concentration through the lungs, it is supposed to go through the digestive system in a highly concentrated form.
Natalie Gray is a Biochemical Engineer. She works in the Research and Development team that focuses on the design and construction of unit processes. She is a recreational marijuana supporter and her love for organic chemistry brought her to medical cannabis. She grows her own flowers, working on different projects and study everything above and under cannabis roots.
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Top 10 Posts from 2016 as chosen by readers of Kiefair.com
Top 10 Posts from 2016 as chosen by readers of Kiefair.com
Below I count down the most read articles from Kiefair.com for the year of 2016. You the reader decide whats really worth reading on this site. I thank you all.
#10
Protect Colorado Springs Home Grows
#9
Hannah Hurnard’s “Hind’s Feet on High Places” audiobook video series
#8
Familial Mediterranean Fever ~ a Rare genetic disease
#7
Phoenix Tears Healing a Diabetic Ulcer (updated Journey)
#6
Hemp Seed and Hemp Seed Oil ~ a superfood, but not a cancer cure…
#5
How to make Cannabis Cure Oil without alerting the neighbors
#4
Cannabis Oil Advocate Ronnie Smith Suddenly Dies from Leukemia
#3
A few words on the properties of Isopropyl alcohol
#2
How to Extract Cannabis Cure Oil with alcohol (Phoenix Tears)
#1
FAQ’s about Phoenix Tears for the Beginner
Questions?
send a pm through facebook to this profile
email: breezyorilley@gmail.com
snail mail:
Bréedhéen O’Rilley Keefer
P.O. Box 849
Franktown, Colorado 80116
Protect Colorado Springs Home Grows
Protect Colorado Springs Home Grows by: Audrey Hatfield
How many registered cannabis patients do you think live in Colorado? How many refugees have given up their former lives to pack up and move here for access to medical cannabis? How many people in general utilize cannabis in some form or another in our state? There are approximately 108,000 registered cannabis patients and out of that many, how many of you have a clue as to what is happening in some city’s across Colorado regarding your rights as a cannabis patient? Very few.
Back in 2012 when the Amendment 64 campaign was rearing its ugly head, I was against it for several reasons. Not because I’m a selfish bitch that didn’t think everyone deserves access to cannabis, it was because, it was and is, a garbage piece of legislative prohibition, designed to benefit our government in the form of higher tax dollars, in disguise as “legalization.” We were all assured by 64 supporters that “medical would not be affected.” A64 was nothing but “legal lies” and too many people lapped it up as “progression” and “baby steps” towards “legalization.” “Regulation works,” “Regulate like alcohol.” Bullshit, all of it, as predicted!
Let’s forget about Amendment 64 for a minute and before you chastise me for using the term “medical cannabis,” there is a difference. That difference is, Amendment 20 and those of us that rely on cannabis as our medicine. For us, it’s not about just “getting high.” And no, I don’t have anything against anyone that does. Cannabis should be available to us all, but not this way. Not thru Amendment 64.
Right now, right under your noses we are slowly being made criminals once again. The MED is “recommending” to all jurisdictions to limit plant counts. One by one, city by city, slowly, Amendment 20 is being blown off by Colorado government officials, in part because of the fact that we have rec and rec generates more tax funds. You might think that it doesn’t matter because we “have A64”. But it does.
In a recent article in local paper the “Gazette Telegraph,” Colorado Springs City Council proposed ordinance 16-52, on May 10, that was signed by Mayor John Suthers, just a few days after on May 13.
In a nut shell, this ordinance (above,) is making it criminal to grow more than 12 plants per household without regard to the fact of ones plant count recommendation (Read above links). Yes, you heard it, it will be CRIMINAL! You will be a CRIMINAL, for exercising your rights under Amendment 20. Pay attention to what this will mean for patients here and eventually in the entire state.
https://coloradosprings.gov/sites/default/files/051016_personal_cultivation_ordinance_16-52.pdf
Colorado Springs is a home rule municipality and basically what that means, is they can make their own rules. HOWEVER, when it comes to this situation they can not decide how many plants a patient is allowed to have! What the fuck? Why is this happening? Amendment 64. Why isn’t it being stopped? Greed and ignorance.
All patients with higher plant counts will be affected, however, the patients that will be hurt the most are some of the many children whose parents moved here to treat their childrens rare illnesses with cannabis. Two of the families that will be affected and turned into criminals if arrested, will be Moms, Rebecca Lockwood and Marisa Kiser. Because of their childrens high plant counts and the negative impact it would have on their childrens health, Rebecca and Marisa, sprung into action. They decided to set up a meeting with City Council to get some answers and find compassion for all patients and spear headed an email campaign to Springs City Council.
Rebecca fears for the health and well-being of her child Calvin, as he has a plant count of 73 to treat his femoral retroversion, a debilitating abnormality, affecting the lower extremities.
http://www.aafp.org/afp/2003/0801/p461.htmlhttps://www.youtube.com/watch?v=T8OYxQq7mIE Marisa Kisers son Ezra, just turned 4 and went in hospice when he was just 3. He suffers from violent seizures and at one time, had an unexplained onset of dystonia so severe that he broke 8 bones in one year. He has a 72 plant count. These are just 2 of the families that will be affected by this bullshit.
It was in a May 31 meeting that the Moms were told by the council members in attendance that, “The limited plants counts are just the beginning, a ban will be placed on all home grows, not just here, but thru out the state.” This very phrase was confirmed the beginning of June from council members in a separate meeting between members of council and member Bridget Serrit, of the newly formed organization, Colorado Patient Rights Coalition
108 million patients and only a handful of you are or have been getting involved with the blatant disregard of our rights. This is going to affect you! Understand what it means! Get off of your asses and stand up for yourselves or bow down to your rights being stepped on by our local politicians. We all need to come together in force and show them that this will not be tolerated! Coming together in numbers will have greater impact and that is what it will take. This WILL happen in your town next, you need to be aware and know your rights as a patient.
Whether you grow or not, what can you do? First, research and familiarize yourselves with Amendment 20 and any laws regarding medical access in Colorado. Send emails to your local government officials that are implementing these laws. Call and leave them a brief, yet detailed message. Stand up for your rights! If you are available during the day, attend any protest about the matter that you see being advertised. Protests are being set up right now in Colorado Springs in front of Mayor Suthers office in Colorado Springs, on a monthly basis. The organization also has started a petition that as patients, you should sign.
https://www.facebook.com/events/266481020371172/https://www.change.org/p/colorado-state-house-keep-it-legal-colorado If you have paperwork to support your plant count recommendation, continue to grow that plant count. If police come to your home, DO NOT, under any circumstances, allow them access inside your home without a search warrant. DO NOT speak to the police. Record audio if they are in your home or at your door. DO NOT be swayed by the scare tactics they will try to use to get you to take a plea deal if you are arrested. You can and will win your case! It has been done! Now more than ever, is the time to get involved! Strength in numbers! Stand up!
http://www.westword.com/news/medical-marijuana-patient-bob-crouse-acquitted-another-wasteful-prosecution-5859198http://www.dailycamera.com/boulder-county-news/ci_16965794
http://gazette.com/jury-returns-not-guilty-verdict-in-mmj-case/article/140056Audrey Hatfield
Former Founder and President of C4CPR
Medical Cannabis Patient and Colorado Activist
Write to city council allcouncil@springsgov.com
Questions?
send a pm through facebook to this profile
email: breezyorilley@gmail.com
snail mail:
Bréedhéen O’Rilley Keefer
P.O. Box 849
Franktown, Colorado 80116
Familial Mediterranean Fever ~ a Rare genetic disease
I do not look like I have a single drop of Mediterranean blood in me, so why do i care about this rare genetic disorder? Because the color of skin is only skin deep. Because despite the pale appearance of my exterior, I have the genetic ancestor from that part of the world who handed me this recessive trait. Because I have this disease and have to live with it…
Breezy Kiefair struggling to gain weight post flare
I care because I need to repost the links as many times as possible in hopes that those related to me by blood will heed my warning and look for signs of the disorder in the kids…. I have made no secret of the fact that I am far estranged from my biological family, so I turn to electronic means to spread the word.
There is no cure, but the treatment does help….. There is no cure, but knowledge that there is indeed something wrong and that I am not a hypochondriac is soothing to the mind…. There is no cure, but it sure as hell does explain a lot about both myself and my blood relatives… BOTH my parents had to have the recessive gene in order for me to have this disorder. Both my parent’s sets of siblings may also be carriers of these recessive traits…. ALL of my blood siblings (half or full blooded) are POTENTIAL carriers of the defect…. Therefore, ALL of my blood nieces and nephews are potential victims of the disease as well as their children. It is my hope that those in my family will stumble upon this post and then value the family’s future generations enough to spread this information to where it may be of use (i emailed it directly to those whose email addresses I possess in my bloodline)
the below information was retrieved from: http://ghr.nlm.nih.gov/condition/familial-mediterranean-fever
What is familial Mediterranean fever?
Familial Mediterranean fever is an inherited condition characterized by recurrent episodes of painful inflammation in the abdomen, chest, or joints. These episodes are often accompanied by fever and sometimes a rash. The first episode usually occurs in childhood or the teenage years, but in some cases, the initial attack occurs much later in life. Typically, episodes last 12 to 72 hours and can vary in severity. The length of time between attacks is also variable. Without treatment to help prevent attacks and complications, a buildup of certain protein deposits (amyloidosis) in the body’s organs and tissues may occur, which can lead to kidney failure.
How common is familial Mediterranean fever?
Familial Mediterranean fever primarily affects populations originating in the Mediterranean region, particularly people of Armenian, Arabic, Turkish, and Jewish ancestry. The disorder affects from 1 in 250 people to 1 in 1,000 people in these populations. It is less common in other populations.
What genes are related to familial Mediterranean fever?
Mutations in the MEFV gene cause familial Mediterranean fever. The MEFV gene provides instructions for making a protein called pyrin (also known as marenostrin), which is found in white blood cells. This protein is involved in the immune system, helping to regulate the process of inflammation. Inflammation occurs when the immune system sends signaling molecules and white blood cells to a site of injury or disease to fight microbial invaders and facilitate tissue repair. When this has been accomplished, the body stops the inflammatory response to prevent damage to its own cells and tissues.
Mutations in the MEFV gene reduce the activity of the pyrin protein, which disrupts control of the inflammation process. An inappropriate or prolonged inflammatory response can result, usually accompanied by fever and pain in the abdomen, chest, or joints.
Normal variations in the SAA1 gene may modify the course of familial Mediterranean fever. Some evidence suggests that a particular version of the SAA1 gene (called the alpha variant) may increase the risk of amyloidosis among people with familial Mediterranean fever.
Read more about the MEFV and SAA1 genes.
How do people inherit familial Mediterranean fever?
Familial Mediterranean fever is almost always inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
In rare cases, this condition appears to be inherited in an autosomal dominant pattern, in which one copy of the altered gene in each cell is sufficient to cause the disorder and affected individuals often inherit the mutation from one affected parent. However, there are other possible explanations of this apparent pattern. A gene mutation that occurs frequently in a population may result in a disorder with autosomal recessive inheritance appearing in multiple generations in a family, a pattern that mimics autosomal dominant inheritance. If one parent has familial Mediterranean fever (with two mutations in the MEFV gene) and the other parent is an unaffected carrier (with one mutation in the MEFV gene), it may appear as if the affected child inherited the disorder only from the affected parent. This appearance of autosomal dominant inheritance when the pattern is actually autosomal recessive is called pseudodominance.
Where can I find information about diagnosis or management of familial Mediterranean fever?
These resources address the diagnosis or management of familial Mediterranean fever and may include treatment providers.
- Gene Review: Familial Mediterranean Fever
- Gene Tests: Familial Mediterranean Fever
- MedlinePlus Encyclopedia: Familial Mediterranean fever
- MedlinePlus Encyclopedia: Secondary systemic amyloidosis
You might also find information on the diagnosis or management of familial Mediterranean fever inEducational resources and Patient support.
To locate a healthcare provider, see How can I find a genetics professional in my area? in the Handbook.
Where can I find additional information about familial Mediterranean fever?
You may find the following resources about familial Mediterranean fever helpful. These materials are written for the general public.
- MedlinePlus – Health information (3 links)
- Genetic and Rare Diseases Information Center – Information about genetic conditions and rare diseases
- Additional NIH Resources – National Institutes of Health (2 links)
- Educational resources – Information pages (3 links)
- Patient support – For patients and families (2 links)
You may also be interested in these resources, which are designed for healthcare professionals and researchers.
- Gene Reviews – Clinical summary
- Gene Tests – DNA tests ordered by healthcare professionals
- ClinicalTrials.gov – Linking patients to medical research
- PubMed – Recent literature
- OMIM – Genetic disorder catalog
What other names do people use for familial Mediterranean fever?
- Benign paroxysmal peritonitis
- Familial paroxysmal polyserositis
- FMF
- Hereditary Periodic Fever Syndromes
- Mediterranean Fever, Familial
- MEF
- Periodic Disease
- Periodic peritonitis
- Recurrent polyserositis
- Reimann periodic disease
- Siegal-Cattan-Mamou disease
- Wolff Periodic Disease
For more information about naming genetic conditions, see the Genetics Home Reference Condition Naming Guidelines and How are genetic conditions and genes named? in the Handbook.
What if I still have specific questions about familial Mediterranean fever?
Where can I find general information about genetic conditions?
The Handbook provides basic information about genetics in clear language.
- What does it mean if a disorder seems to run in my family?
- What are the different ways in which a genetic condition can be inherited?
- If a genetic disorder runs in my family, what are the chances that my children will have the condition?
- Why are some genetic conditions more common in particular ethnic groups?
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding familial Mediterranean fever?
amyloidosis ; autosomal ; autosomal dominant ; autosomal recessive ; benign ; carrier ; cell ; complication ;familial ; fever ; gene ; immune system ; inflammation ; inheritance ; injury ; joint ; kidney ; molecule ;mutation ; population ; protein ; pseudodominance ; recessive ; sign ; symptom ; syndrome ; teenage ;tissue ; white blood cells
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.
please also read:
http://emedicine.medscape.com/article/330284-overview#showall
Familial Mediterranean fever
Familial Mediterranean fever (FMF) is a hereditary inflammatory disorder[1]:149. FMF is an autoinflammatory disease caused by mutations in MEFV, a gene which encodes a 781–amino acid protein denoted pyrin.[2]
The disorder has been given various names including familial paroxysmal polyserositis, periodic peritonitis, recurrent polyserositis, benign paroxysmal peritonitis, periodic disease or periodic fever, Reimann periodic disease or Reimann’s syndrome, Siegal-Cattan-Mamou disease, and Wolff periodic disease.[3][4][5] Note that “periodic fever” can also refer to any of thePeriodic fever syndromes.
Epidemiology
FMF affects groups of people originating from around the Mediterranean Sea (hence its name). It is prominently present in the Armenian people, Sephardi Jews (and, to a much lesser extent, Ashkenazi Jews), Cypriots, Turks and Arabs.[6]
[edit]Signs and symptoms
[edit]Attacks
There are seven types of attacks. Ninety percent of all patients have their first attacks before they are 18 years old. All develop over 2–4 hours and last anywhere from 6 hours to 4 days. Most attacks involve fever.[6]
- Abdominal attacks, featuring abdominal pain, affect the whole abdomen with all signs of peritonitis (inflammation of abdominal lining), and acute abdominal pain likeappendicitis. They occur in 95% of all patients and may lead to unnecessary laparotomy. Incomplete attacks, with local tenderness and normal blood tests, have been reported.
- Joint attacks mainly occur in large joints, especially in the legs. Usually, only one joint is affected. Seventy-five percent of all FMF patients experience joint attacks.
- Chest attacks include pleuritis (inflammation of the pleura) and pericarditis (inflammation of the pericardium). Pleuritis occurs in 40% of patients, and makes it difficult to breathe or lie flat, but pericarditis is rare.
- Scrotal attacks due to inflammation of the tunica vaginalis occurs in up to 5% and may be mistaken for acute scrotum (i.e. testicular torsion).
- Myalgia (rare in isolation)
- Erysipeloid (a skin reaction on the legs, rare in isolation)
- Fever without any of the other symptoms listed above (25%)
[edit]Complications
AA-amyloidosis with renal failure is a complication and may develop without overt crises. AA amyloid protein is produced in very large quantities during attacks, and at a low rate between them, and accumulates mainly in the kidney, as well as the heart, spleen, gastrointestinal tract and thyroid.[6]
There appears to be an increase in the risk for developing particular vasculitis-related diseases (e.g. Henoch-Schönlein purpura), spondylarthropathy, prolonged arthritis of certain joints and protracted myalgia.[6]
[edit]Diagnosis
The diagnosis is clinically made on the basis of the history of typical attacks, especially in patients from the ethnic groups in which FMF is more highly prevalent. An acute phase response is present during attacks, with high C-reactive protein levels, an elevated white blood cell count and other markers of inflammation. In patients with a long history of attacks, monitoring the renal function is of importance in predicting chronic renal failure.[6]
A genetic test is also available to detect mutations in the MEFV gene. Sequencing of exons 2, 3, 5, and 10 of this gene detects an estimated 97% of all known mutations.[6]
A specific and highly sensitive test for FMF is the “Metaraminol Provocative Test (MPT),” whereby a single 10 mg infusion of Metaraminol is administered to the patient. A positive diagnosis is made if the patient presents with a typical, albeit milder, FMF attack within 48 hours. As MPT is more sensitive than specific, it does not identify all cases of FMF. Although a positive MPT can be very useful.[7][8]
[edit]Pathophysiology
Virtually all cases are due to a mutation in the MEFV gene on the sixteenth chromosome, which codes for a protein called pyrin or marenostrin. Various mutations of this gene lead to FMF, although some mutations cause a more severe picture than others. Mutations occur mainly in exons 2, 3, 5 and 10.[6]
The function of pyrin has not been completely elucidated, but it appears to be a suppressor of the activation of caspase 1, the enzyme that stimulates production of interleukin 1β, a cytokine central to the process of inflammation. In other words an ineffective pyrin doesn’t inhibit inflammation normally, resulting in inflammatory episodes of membranes at differing sites. It is not conclusively known what exactly sets off the attacks, and why overproduction of IL-1 would lead to particular symptoms in particular organs (e.g. joints or the peritoneal cavity).[6]
[edit]Genetics
Familial Mediterranean fever has an autosomal recessive pattern of inheritance.
The MEFV gene is located on the short arm of chromosome 16 (16p13). The disorder inherits in an autosomal recessive fashion. Therefore, two asymptomatic carrier parents have a 25% chance of a child with the disorder, a 50% chance of a child who is an asymptomatic carrier and a 25% chance of a child who does not carry the disorder. FMF patients who have children with a carrier or another FMF patient have a 50% and 100% chance, respectively, of having a child with FMF.[9][10]
There is one known case of an affected patient with only one parent who is a carrier. This is caused by a unique mutation on thesixteenth chromosome.
[edit]Treatment
Attacks are self-limiting, and require analgesia and NSAIDs (such as diclofenac).[6]
Colchicine, a drug otherwise mainly used in gout, decreases attack frequency in FMF patients. The exact way in which colchicine suppresses attacks is unclear. While this agent is not without side effects (such as abdominal pain and muscle pains), it may markedly improve quality of life in patients. The dosage is typically 1–2 mg a day. Development of amyloidosis is delayed with colchicine treatment. Interferon is being studied as a therapeutic modality.[6] Some advise discontinuation of colchicine before and during pregnancy, but the data are inconsistent, and others feel it is safe to take colchicine during pregnancy.[11]
Approximately 5-10% of FMF cases are resistant to colchicine therapy alone. In these cases, adding anakinra to the daily colchicine regimen has been successful.[12]
[edit]History
A New York allergist, Dr Sheppard Siegal, first described the attacks of peritonitis in 1945; he termed this “benign paroxysmal peritonitis”, as the disease course was essentially benign.[13] Dr Hobart Reimann, working in the American University in Beirut, described a more complete picture which he termed “periodic disease”.[14][15]
In 1972, colchicine was discovered to prevent attacks.[16]
The link to the MEFV gene was discovered in 1997 by two different groups, each working independently – the French FMF Consortium,[9] and the International FMF Consortium.[10]
[edit]See also
[edit]References
- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews’ Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ^ Chae JJ, Wood G, Richard K et al. (September 2008). “The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment”. Blood 112 (5): 1794–1803. doi:10.1182/blood-2008-01-134932. PMC 2518886. PMID 18577712.
- ^ Dugdale III, David C; Jatin Vyas (2010-09-15). “Familial Mediterranean fever – PubMed Health”. PubMed Health. National Centre for Biotechnology Information. Retrieved 2011-04-24.
- ^ Enersen, Ole Daniel. “Whonamedit – Siegal-Cattan-Mamou syndrome”. Whonamedit? A dictionary of medical eponyms. Archived from the original on 2001-04-24. Retrieved 2011-04-24.
- ^ “Familial Mediterranean fever – Genetics Home Reference”. Genetics Home Reference. U.S. National Library of Medicine. 2011-04-14. Archived from the original on 2011-04-24. Retrieved 2011-04-24.
- ^ a b c d e f g h i j Livneh A, Langevitz P (2000). “Diagnostic and treatment concerns in familial Mediterranean fever”. Baillieres Best Pract Res Clin Rheumatol 14 (3): 477–498.doi:10.1053/berh.2000.0089. PMID 10985982.
- ^ Barakat MH, El-Khawad AO, Gumaa KA, El-Sobki NI, Fenech FF (1984). “Metaraminol provocative test: a specific diagnostic test for familial Mediterranean fever”. Lancet 1(8378): 656–7. PMID 6142351.
- ^ Huppertz HI, Michels H (1988). “[The metaraminol provocation test in the diagnosis of familial Mediterranean fever]”. Monatsschr Kinderheilkd 136 (5): 243–5. PMID 3405225.
- ^ a b The French FMF Consortium (1997). “A candidate gene for familial Mediterranean fever”. Nat. Genet. 17 (1): 25–31. doi:10.1038/ng0997-25. PMID 9288094.
- ^ a b The International FMF Consortium (1997). “Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever”. Cell 90(4): 797–807. doi:10.1016/S0092-8674(00)80539-5. PMID 9288758.
- ^ Michael O, Goldman RD, Koren G (August 2003). “Safety of colchicine therapy during pregnancy”. Can Fam Physician 49: 967–9. PMC 2214270. PMID 12943352.
- ^ Calligaris L, Marchetti F, Tommasini A, Ventura A (2008). “The efficacy of anakinra in an adolescent with colchicine-resistant familial Mediterranean fever”. European Journal of Pediatrics 167 (6): 695–696. doi:10.1007/s00431-007-0547-3. PMC 2292480. PMID 17588171.
- ^ Siegal S (1945). “Benign paroxysmal peritonitis”. Ann Intern Med 23 (2): 234–47. PMID 18124924.
- ^ Reiman HA (1948). “Periodic disease. Probable syndrome including periodic fever, benign paroxysmal peritonitis, cyclic neutropenia and intermittent arthralgia”. J Am Med Assoc 136 (4): 239–44. PMID 18920089.
- ^ synd/2503 at Who Named It?
- ^ Goldfinger, S.E. (1972-12-21). “Colchicine for familial Mediterranean fever”. New England Journal of Medicine 287 (25): 1302. doi:10.1056/NEJM197212212872514.PMID 4636899.
[edit]External links
- Proteopedia 2wl1 information about the MEFV gene.
- GeneReview/NIH/UW entry on Familial Mediterranean Fever
Breezy Says:
–Auto signature below–
Respectfully,
Breedheen O’Rilley Keefer
AKA Breezy Kiefair
links about breezy
blog
http://misshightimes.com/users/breezykiefair
on youtube
http://www.youtube.com/user/Mr8MrsKiefAir?feature=mhsn
art “like” page on FB
http://www.facebook.com/pages/The-Art-of-Breezy-Kiefair/154533251224064
fb profile
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@breezykiefair
the short 4 page version:
http://www.scribd.com/doc/64585079/My-Personal-Christmas-Present-to-the
shine out from you, and plant the seed of peace in other spirits, for them
to cultivate.~{Remember… it is when we choose act on the issues that are in front of
our faces, when we choose to get involved instead of looking the other way
as our fellow man struggles, when we choose to take those small simple
little actions, working on righting little wrongs in our everyday lives that
really make change happen, those seemingly small actions are what really
make the world a better place and are a catalyst for greater social change.}
~Both quotes by Breedheen “Bree” O’Rilley Keefer~
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- Colchicine in Renal Failure (sajerosablog.wordpress.com)
- Interesting article about CVID and Genes (cvidarticles.wordpress.com)
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At Home Baked Baked at home revisited: Gluten Free & Blondie
June 15, 2012
Gluten Free Medicated Brownies from At Home Baked
video review: At Home Baked LLC’s Gluten Free medicated brownies read the previous review here http://breedheenorilleykeefer.com/2012/04/04/at-home-baked-baked-at-home/
You can find out where you can pick up a box of brownie mix at the At Home Baked website. http://www.athomebakedcolorado.com/
other reviews and testimonials of this product: http://www.athomebakedcolorado.com/patient-reviews-testimonials/ http://nugs.com/article/edibles-review-at-home-baked-brownie-mix.html NEW REVIEW VIDS TO FOLLOW! __________________________________________________
June 17, 2012
Baking the Blondies from At Home Baked
please read this article on the benefits of hemp seed!
Review
2012-06-18 at home baked blondies review 10 of 10!
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
I’ll end with my previous review of At Home Baked
*****NOTE***** when I wrote this, I had an UN-DIAGNOSED BROKEN PELVIS!
At Home Baked, Baked at Home Before I begin my review of these brownies, let me set the stage… It’s spring in the Colorado Rockies. We’ve had some lovely weather, and I have overexerted myself into intractable pain. A storm begins to move over the mountains threatening our warm weather. I’ve been pushing through the intractable pain and working with the aid of cannabis hash oil made in the Rick Simpson method, but am still aching. I watch the storm growing ever closer and begin to wish for sleep. Then I remember a gift from ReverendPartridge. I happen to have a box of indica “At Home Baked” Brownies. The good reverend had put them into my hands as a mercy and asked me to try them. So, I hobble into the kitchen with my box of compassion to bake up some mercy. I read the instructions on the box which are as follows:
Baking Instructions
For your At Home Baked experience you need:
A Box of At Home Baked Brownies or Blondies
2 eggs
a little butter or oil to grease baking pan
an 8×8 or 9×9 baking pan
a large mixing bowl
mixing spoon or whisk
- Pre-heat oven to 350 degrees.
- Grease 8×8 or 9×9 baking pan.
- Place dry ingredients into large mixing bowl.
- Shake oil packet then add and mix evenly (about 20 strokes)
- Add eggs one at a time and finish mixing (30 more strokes)
- Spread mixed batter into baking pan.
- Bake @ 350 Degrees until center sets Approx. 25-35min in 8×8 or 20-30min in 9×9 pan
- Let cool then enjoy with caution!
A little goes a long way!
If you aren’t sure weather they are done or not use a toothpick and poke the middle of the mix if it is mostly clean they are done if it is covered in fudgy goodness they need a few more minuets.
(retrieved from: http://www.athomebakedcolorado.com/baking-instructions/ )
About ten minutes later, they were in the oven, about a half an hour after that, they came out of the oven. I cut the brownies into 8 pieces as directed by the box. As soon as they were cool enough, I plated the brownies and some fresh strawberries and a cup of tea. The brownie’s flavor was decadent rich chocolate on the palate with the familiar notes of cannabis in proper balance with the other flavors. It was enjoyable to eat, but so rich I would recommend you have a drink handy when you serve one to yourself or your patient. Most people would say a glass of milk, but I opted for some tea. I was still awake and in pain an hour and a half later, however I was also capable of laughter. I had not been capable of laughing in some time. This was an improvement. Eager and hoping to achieve an end to the intractable pain shooting through my body, I plated up another brownie. Just as I began munching on the second brownie, snow began falling and I understood why I was having issue getting on top of my pain. It had to be the impending storm making it so difficult to get comfortable. In the end, I ate a nearly half a pan of brownies. I was up most of the night, but once the storm slowed and I found sleep, I did sleep for an increased duration compared with my usual sleep patterns. Before you think this is a negative review, let me remind you of the definition of intractable:
Definition of INTRACTABLE
1
: not easily governed, managed, or directed <intractable problems>
2
: not easily manipulated or wrought<intractable metal>
3
: not easily relieved or cured <intractable pain>
(retrieved from: http://www.merriam-webster.com/dictionary/intractable )
The fact that these brownies were able to make me laugh when I was in so much pain is a strong indication to me of a good product. Another Carded individual in the house was asleep within 30 minutes of eating 1 brownie. My assessment, 10 of 10 Medicinal Leaves Awarded! You can find out where you can pick up a box of brownie mix at the At Home Baked website. http://www.athomebakedcolorado.com/
other reviews and testimonials of this product: http://www.athomebakedcolorado.com/patient-reviews-testimonials/ http://nugs.com/article/edibles-review-at-home-baked-brownie-mix.html
_____________________________________________________________
latest fat freddy video:
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Related articles
- At Home Baked, Baked at Home (breedheenorilleykeefer.com)
- The History of Brownies in the United States (berries.com)
At Home Baked, Baked at Home
At Home Baked, Baked at Home
Before I begin my review of these brownies, let me set the stage… It’s spring in the Colorado Rockies. We’ve had some lovely weather, and I have overexerted myself into intractable pain. A storm begins to move over the mountains threatening our warm weather. I’ve been pushing through the intractable pain and working with the aid of cannabis hash oil made in the Rick Simpson method, but am still aching. I watch the storm growing ever closer and begin to wish for sleep.
Then I remember a gift from Reverend Partridge. I happen to have a box of indica “At Home Baked” Brownies. The good reverend had put them into my hands as a mercy and asked me to try them. So, I hobble into the kitchen with my box of compassion to bake up some mercy.
I read the instructions on the box which are as follows:
Baking Instructions
For your At Home Baked experience you need:
A Box of At Home Baked Brownies or Blondies
2 eggs
a little butter or oil to grease baking pan
an 8×8 or 9×9 baking pan
a large mixing bowl
mixing spoon or whisk
- Pre-heat oven to 350 degrees.
- Grease 8×8 or 9×9 baking pan.
- Place dry ingredients into large mixing bowl.
- Shake oil packet then add and mix evenly (about 20 strokes)
- Add eggs one at a time and finish mixing (30 more strokes)
- Spread mixed batter into baking pan.
- Bake @ 350 Degrees until center sets Approx. 25-35min in 8×8 or 20-30min in 9×9 pan
- Let cool then enjoy with caution!
A little goes a long way!
If you aren’t sure weather they are done or not use a toothpick and poke the middle of the mix if it is mostly clean they are done if it is covered in fudgy goodness they need a few more minuets.
(retrieved from: http://www.athomebakedcolorado.com/baking-instructions/ )
About ten minutes later, they were in the oven, about a half an hour after that, they came out of the oven. I cut the brownies into 8 pieces as directed by the box. As soon as they were cool enough, I plated the brownies and some fresh strawberries and a cup of tea.
The brownie’s flavor was decadent rich chocolate on the palate with the familiar notes of cannabis in proper balance with the other flavors. It was enjoyable to eat, but so rich I would recommend you have a drink handy when you serve one to yourself or your patient. Most people would say a glass of milk, but I opted for some tea.
I was still awake and in pain an hour and a half later, however I was also capable of laughter. I had not been capable of laughing in some time. This was an improvement. Eager and hoping to achieve an end to the intractable pain shooting through my body, I plated up another brownie. Just as I began munching on the second brownie, snow began falling and I understood why I was having issue getting on top of my pain. It had to be the impending storm making it so difficult to get comfortable. In the end, I ate a nearly half a pan of brownies. I was up most of the night, but once the storm slowed and I found sleep, I did sleep for an increased duration compared with my usual sleep patterns.
Before you think this is a negative review, let me remind you of the definition of intractable:
Definition of INTRACTABLE
1
: not easily governed, managed, or directed <intractable problems>
2
: not easily manipulated or wrought<intractable metal>
3
: not easily relieved or cured <intractable pain>
(retrieved from: http://www.merriam-webster.com/dictionary/intractable )
The fact that these brownies were able to make me laugh when I was in so much pain is a strong indication to me of a good product. Another Carded individual in the house was asleep within 30 minutes of eating 1 brownie.
My assessment, 10 of 10 Medicinal Leaves Awarded!
You can find out where you can pick up a box of brownie mix at the At Home Baked website.
http://www.athomebakedcolorado.com/
other reviews and testimonials of this product:
http://www.athomebakedcolorado.com/patient-reviews-testimonials/
http://nugs.com/article/edibles-review-at-home-baked-brownie-mix.html
Kiefair.com DIY cannabis and more 